In fact, this issue is a cliché, and I have already mentioned it in the “FAQ on multiple myeloma” to patients and their families. I would like to emphasize it here. Patients with multiple myeloma should not take any “big supplements” in their daily life! Constipation is one of the adverse effects of Reactivation, a drug commonly used in multiple myeloma. Constipation is one of its adverse effects. If there is excess nutrition, it will lead to more constipation. Yang Guangzhong, Department of Hematology, Beijing Chaoyang Hospital Dexamethasone is also one of the effective drugs for the treatment of this disease. Before the disease is effectively controlled, the so-called “supplements” are mostly used by the dominant myeloma cells! In addition, patients are prone to gastrointestinal reactions during chemotherapy, so it is advisable to have a light diet to facilitate intestinal absorption and utilization. The diet should be hygienic to avoid causing gastrointestinal infections, for example, the morning meal should not be left for noon and then eaten. Reduce the intake of soy products (soy milk, tofu brain, etc.), especially in patients with renal insufficiency, because soy foods contain non-essential amino acids that may damage the kidneys. Even if the kidney function is normal, it is recommended that myeloma patients should be careful. During their recovery process, myeloma patients should pay attention to eat less acidic foods, such as tomatoes, hawthorn and vinegar, so as not to cause abnormal immunoglobulin precipitation and increase the burden on the kidneys. Patients can appropriately eat more foods with high active calcium, such as milk and bone broth, to increase calcium intake and relieve osteoporosis.