Safflower oil should not be applied on the face to avoid some irritating effects. Safflower oil is mainly used for the relief of rheumatic bone pain, some joint parts or sprains, or external headaches can be used for the head, but definitely not on the face. Because some of the ingredients in safflower oil such as methyl salicylate, cinnamon oil, cinnamaldehyde, citral, ice chips, ginger camphor oil, clove, basil oil, etc., these drugs are sometimes applied to the face after the hot and spicy feeling, including some patients are prone to some skin allergy symptoms, so safflower oil must not be applied to the face. If an allergic reaction occurs, it must be stopped in time and some anti-allergy medication must be used quickly to relieve the symptoms. If the symptoms are not relieved by anti-allergy medication, then promptly go to the hospital for treatment.