The pain is always in the thumb: 1. If there is an obvious small bump under the thumb, it may be related to the tendon sheath cyst of the thumb. 2. If it is related to the nature of the patient’s work, it may be a painful performance caused by the frequent use of the thumb. 3. 4. If the pain occurs after drinking alcohol, the possibility of gout cannot be ruled out. Therefore, if the above situation occurs, you must go to a regular hospital orthopedic examination in a timely manner, according to the auxiliary examination combined with the cause of the disease, and then confirm the diagnosis after treatment according to medical advice, do not delay the condition.