Rheumatology is a young clinical medical discipline, and because of its late start, people’s knowledge of rheumatism is still shallow, which can easily lead to underdiagnosis and misdiagnosis. Rheumatic diseases refer to diseases that mainly affect joints, muscles, bones and soft tissues around joints, such as tendons, ligaments, bursae and fascia. The common ones are autoimmune connective tissue disease, systemic vasculitis, bone and joint lesions, so the common symptoms are: 1. Fever is a common symptom of rheumatic diseases, which can be low fever, moderate fever, or high fever, often manifested as irregular fever, usually without chills, antibiotics are ineffective, while the blood sedimentation is fast, such as systemic lupus erythematosus, adult Stearns disease, acute neutrophilic febrile dermatosis, seborrhea Fever can be the first symptom of systemic lupus erythematosus, adult Steyr disease, acute neutrophilic febrile dermatosis and seborrhea. 2. Pain is the main symptom of rheumatic diseases and an important cause of functional impairment. Among the pain of rheumatic diseases, pain originating from joints and their appendages is the most common, but pain in the limbs and trunk can also be seen in visceral and neurological lesions. Joint pain, neck and shoulder pain, low back pain, and heel pain are often the main manifestations of rheumatism, sometimes accompanied by swelling of the joints. Rheumatoid arthritis often has symmetrical joint swelling and pain, especially in the finger joints and wrist joints; ankylosing spondylitis has low back pain, which is aggravated at rest, and may be accompanied by heel pain and red eyes; rheumatic polymyalgia has neck and shoulder pain, pain in the limb band muscles and muscle weakness. 3, skin and mucous membrane symptoms: systemic lupus erythematosus, dermatomyositis/polymyositis, leukodystrophy, lipofuscinosis, dry syndrome may have rash, photosensitivity, oral ulcers, vulvar ulcers, eye symptoms, reticular cyanosis, skin ulcers, etc. 4. Raynaud’s sign: whitening of the finger (toe) ends when exposed to cold or emotional agitation, followed by purple and red or accompanied by numbness and pain at the finger (toe) ends, and severe skin ulceration, which can be seen in scleroderma, rheumatoid arthritis, mixed connective tissue disease, and systemic lupus erythematosus. 5, muscle may have muscle pain, muscle weakness, elevated muscle enzymes, electromyography shows myogenic damage, such as dermatomyositis / polymyositis, mixed connective tissue disease, systemic lupus erythematosus, etc. 6. Systemic damage: Some rheumatic diseases, especially autoimmune connective tissue diseases such as systemic lupus erythematosus and rheumatoid arthritis, can have damage to multiple organs, such as manifesting as cardiac inflammation (pericarditis, myocarditis, endocarditis), renal damage (proteinuria, hematuria, swelling, hypertension, renal failure), hematologic system (leukopenia, erythrocytopenia, thrombocytopenia, capacitated blood, etc.), the Respiratory system (interstitial pneumonia, pulmonary hypertension, pleural effusion), digestive system (liver function impairment, jaundice), etc. 7, often have autoantibodies: anti-nuclear antibodies, anti-ds-DNA antibodies, anti-ENA antibodies, anti-platelet antibodies, anti-cardiolipin antibodies, rheumatoid factor, etc.