The evolutionary process from gastric disease to gastric cancer is complicated in the clinical setting, but from clinical experience or research, the evolutionary process that occurs includes four steps: 1. chronic superficial gastritis. 2. development of chronic atrophic gastritis. 3. appearance of atypical intestinal epithelial chemosis heterogeneous hyperplasia. 4. gradual shift from mild atypical hyperplasia to severe atypical hyperplasia, possibly under the action of multiple triggers, and finally development of The possibility of gastric cancer. The development from chronic atrophic gastritis to gastric cancer is a one-way development trend and irreversible. To reduce or prevent the occurrence of gastric cancer, we should start from the prevention of gastric disease.