A dog bite after rabies vaccination may still infect a person with the rabies virus and lead to rabies. The usual clinical advice for bites from rabies-vaccinated dogs is to follow the principles of rabies post-exposure management, to clean and disinfect the wound properly and to vaccinate against rabies. This is because it is not certain that the dog can produce effective immunity after vaccination, animal rabies vaccine needs to be vaccinated every six months, must be vaccinated consecutively on schedule, if the interval is too long, it is very likely to lead to the disappearance of antibodies in the dog’s body. Rabies vaccination only prevents the dog from developing rabies, but does not guarantee that the dog does not carry the rabies virus in its body. Therefore, after being bitten, it is necessary to treat the wound in accordance with the standard requirements and inoculate the dog with rabies vaccine and rabies immune globulin.