Convex palate is a clinical manifestation of craniosynostosis in Marfontein syndrome. The disease is inherited in an autosomal dominant manner. Mucopolysaccharides such as chondroitin sulfate A or C accumulate in many tissues of the body, such as the endocardium, heart valves, large blood vessels, and bones, thereby affecting the structure and function of elastic fibers and other connective tissue fibers, resulting in dysplasia and functional abnormalities in the corresponding organs. Marfontein syndrome is also known as congenital mesodermal dysplasia, Marchesani syndrome, spider sign, and limb elongation. The main manifestations are peripheral connective tissue dystrophy, skeletal abnormalities, inner eye disease and cardiovascular abnormalities, and it is a hereditary disease in which connective tissue is the basic defect. So what are the preventive measures? 1.The main purpose of drug treatment for Mafang syndrome is to slow down or delay the occurrence of cardiovascular lesions and to prevent and treat ventricular arrhythmias. 2, regular follow-up review, lifelong application of beta-blocker drugs. 3.Restriction of heavy physical activity can slow and delay the onset and development of cardiovascular lesions.