The physiological roles of estrogen are mainly to promote the development and maturation of female internal and external reproductive organs and breasts, to promote the development of the uterus, to cause the endometrium to proliferate, to maintain female secondary sexual characteristics, to stimulate follicular development, and to regulate and control the hormone secretion of the hypothalamus and pituitary gland. In addition, about 200 organs throughout the body have estrogen receptors that receive estrogen action, such as estrogen also has the role of regulating fat metabolism, which is conducive to preventing atherosclerosis, protecting the heart and preventing coronary heart disease; maintaining normal bone mass, preventing osteoporosis, and delaying the aging of skin, teeth and eyes. It promotes the growth of nerve cells in the brain and prevents brain degeneration and early senile dementia. The physiological role of progesterone is mainly to act on the endometrium to further develop the hyperplastic endometrium and produce secretion, making it favorable for fertilized eggs to be laid and grow and develop, and to promote the development and maturation of mammary gland follicles based on the action of estrogen. In addition, progesterone affects the secretion of hormones in the hypothalamus and pituitary gland and excites the hypothalamic thermoregulatory center, causing the body temperature to rise.