HER2 Exon20 gene mutation means a mutation in exon 20 of the HER2 gene, which is commonly used to guide targeted therapy for malignant tumors.
HER2 gene is a proto-oncogene located on human chromosome 17, which is not pathogenic under normal conditions, but can be transformed into an oncogene under the action of physical, chemical, biological and other external environments, thus inducing cells to undergo abnormal proliferation and carcinogenesis.
Exon is the English expression for exon, which belongs to the coding region of a gene and can encode proteins, thus affecting the biological function of cells.
HER2 Exon20 gene mutation, i.e. mutation in exon 20 of the HER 2 gene, belongs to cytogenetic level changes and is often detected by second-generation gene sequencing, which can occur in breast cancer, lung cancer and other cancers, and is of great significance in guiding targeted therapies.
Gene testing is highly specialized, so it is recommended that patients should consult hospitals in time and under the guidance of specialists to carry out relevant gene testing and active diagnosis and treatment, so as to avoid delaying their conditions.