Lupus erythematosus can be vaccinated with hpv vaccine, but it needs to be vaccinated when the disease control is relatively stable, and it is recommended that the doctor’s opinion prevails. Lupus erythematosus is a common autoimmune disease, which can be caused by genetics, immune abnormality, endocrine abnormality, infection and other etiological factors; while Hpv vaccine is used to prevent cervical cancer caused by human papillomavirus infection, and it is also a common type of vaccine. Therefore, if lupus erythematosus is in the stage of disease progression, the HPV vaccination is not allowed, which may aggravate the disease manifestation and affect the effect of the vaccine at the same time. However, if the disease is in a stable stage and under good control, the HPV vaccination can be administered. It is advisable to consult your doctor for specific advice.