For patients with type 2 diabetes mellitus if a time without insulin, the result may lead to a transient increase in sugar levels, but will not cause much impact on the body, as long as to ensure that the follow-up can adhere to the treatment of insulin, the diabetes of blood glucose control will not have an impact. However, if the impact on the body of type 1 diabetes patients who do not take insulin at one time is more significant, it may lead to a significant increase in blood glucose, or even induce ketoacidosis. Because type 1 diabetes belongs to insulin-dependent diabetes, if a time without insulin is very easy to lead to ketosis or ketoacidosis, so the diabetic patient whether it is type 1 diabetes, or type 2 diabetes should be in accordance with the doctor’s instructions to adhere to the use of insulin, try not to miss.