Puffiness in a woman’s face may be caused by physiological factors, as well as pathological causes such as hypothyroidism and acute glomerulonephritis. Depending on the cause, it can be treated by general treatment, medication and dialysis. 1. Physiological factors: Normal women may have swollen face when they wake up in the morning due to excessive intake of water before going to bed and long term intake of high salt food, etc. It can be improved by reducing the amount of water before going to bed and avoiding high salt food such as seaweed and smoked food, etc. to improve the lifestyle. 2. Hypothyroidism: Hypothyroidism in women leads to a decrease in thyroid hormones, resulting in impaired protein metabolism and mucous edema, which manifests itself as facial edema. If necessary, supplemental levothyroxine tablets can be used as replacement therapy. 3. Acute glomerulonephritis: Acute glomerulonephritis can lead to thickening of the glomerular basement membrane, reduced glomerular filtration function, sodium retention, resulting in facial edema. It can be treated by using furosemide, spironolactone and other diuretics to reduce swelling, but also follow the doctor’s instructions to take penicillin to reduce the severity of glomerulonephritis, and dialysis can also be chosen if necessary. The reason for the swelling of the woman’s face is also related to heart failure, renal insufficiency and other factors, the patient should go to the hospital in a timely manner to improve the examination, clear cause of the disease to give targeted treatment in accordance with the doctor’s instructions.