Rhône disease is a chronic, recurrent and nonspecific transmural inflammatory disease of the GI tract with a segmental distribution that can involve any part of the GI tract, with the terminal ileum being the most common and the colon and anus being more frequently affected. The disease may also be associated with extra-intestinal manifestations in the skin, eyes and joints. In addition, what other features does Crohn’s disease have? Diarrhea is a common manifestation of Crohn’s disease. Most of the patients have frequent and watery stools daily, and when the rectum is involved, it can manifest pus and blood and a feeling of urgency. Second, fever and chills, will destroy the absorption of tissue toxins and cause the performance of fever, positive and evil, mostly reflecting high fever, chills and other toxic blood performance. Third, pain appears in the right lower abdomen and is associated with terminal ileal lesions, which are characterized by abdominal pain associated with gastrointestinal reflexes. Plasma membrane involvement, peri-intestinal abscess, intestinal adhesions and intestinal obstruction, intestinal perforation and acute peritonitis as well as toxic megacolon can cause abdominal pain. Perianal lesions: perianal lesions include perianal fistula, abscess formation and anal fissure, which are seen in some patients and are more common in those with colonic involvement. Sometimes these lesions can be the first or prominent clinical manifestation of the disease. What is important to know is that the disease is not effectively controlled and surgical treatment of perianal and perirectal lesions alone is ineffective. Fifth, in addition, there are some manifestations outside the visible intestinal tract, such as nausea, vomiting, poor nausea, weakness, slight thinness, anemia, hypoalbuminemia, and other nutritional obstruction and extraintestinal manifestations as well as clinical manifestations caused by complications. Therefore, early detection of the disease, we must promptly go to the regular hospital for examination, early examination early standardized treatment early recovery.