If you feel worms in your anus, consider the possibility of pinworm disease. Pinworm disease is an intestinal parasitic disease characterized by itching in the anus and perineum, and is extremely prevalent around the world, and is widespread in the south and north of China, with a higher rate of infection in children than in adults. Domestic survey data show that in families with poor hygiene conditions, children often have most of their members sick at the same time, so pinworm disease is a disease that deserves attention. People are the only host of pinworms, and pinworm-infected people are the only source of pinworm disease, and there are two modes of infection: self-infection and heterologous infection. The self-infection is that the female crawls in the anus at night and lays eggs on the surrounding skin, causing itchiness. If the eggs hatch at the anal opening, they can also cause retrograde infection. These two self-infection modes aggravate the infection and make it persistent. Allogeneic infection is transmitted orally through food and toys contaminated with eggs, and can also be contracted by inhaling the flying eggs through the mouth and nose and then swallowing them, which is the main way of causing collective to interfamilial transmission. If the diagnosis is clear, the oral medication intestinal wormer or mebendazole is more effective.