Infection in the submandibular space must be treated with anti-infection, and broad-spectrum antibiotics can be applied, commonly used amoxicillin, clindamycin, cephalosporin antibiotics or quinolone antibiotics and so on. At the same time, it is recommended to cooperate with the application of metronidazole, tinidazole and other anti-anaerobic drugs, which may also be caused by anaerobic bacterial infections in the oral cavity. Topical anti-inflammatory ointment can be given on the red and swollen skin surface, such as clindamycin ointment, Bactroban or ointment made of traditional Chinese medicine, commonly used seven flavors detoxification ointment or Pientzehuang ointment, which have very good anti-inflammatory and pain-relieving effects. If localized abscess formation occurs, incision and drainage of pus must be given in order to improve quickly.