Kidney cancer interventional treatment methods

  Kidney cancer occupies the third place among genitourinary tumors, and radical surgery is the main treatment for kidney cancer. However, because of the insidious onset of kidney cancer, 25% of patients have lost the opportunity of surgery when diagnosed, especially for patients with local or distant metastases in the middle and late stage of kidney cancer, there is a lack of effective clinical treatment measures, and surgery is difficult, and even if the kidney cancer is surgically resected, the prognosis is often poor; because the conventional radiotherapy, chemotherapy, hormone and immunotherapy have limited efficacy on kidney cancer, therefore, the 1-year survival rate of those who cannot be operated with simple palliative treatment is less than 10%. survival rate is less than 10%.  Renal artery embolization was first reported in 1969, but it was not until the mid-1970s that renal artery embolization was widely used in the treatment of kidney cancer, especially advanced kidney cancer. In China, anhydrous alcohol – iodinated oil emulsion is used for the treatment of renal cancer via intraductal embolization. The action of anhydrous alcohol on the target organ can reach the capillary level, causing tissue protein coagulation, vascular endothelial destruction and blood cell stagnation in small vessels, resulting in permanent embolization, which is not easy to form collateral circulation. The combined application of iodinated oil and anhydrous alcohol has a mutually reinforcing effect: the former can delay the action of the latter on the target organ, while the latter can delay the clearance of the former in the lesion, and the combined application of the two can be followed by X-ray, which is conducive to monitoring the embolization process and follow-up observation. Embolization shows symptom relief, interruption of tumor blood supply, volume reduction, disappearance of hematuria, pain relief, and can lead to complete tumor necrosis in most patients (especially those with small tumors) with positive efficacy. With the advancement of technology, it is possible to inactivate the tumor locally and achieve the effect of surgical “resection”, which is expected to prolong the life span of patients and improve the quality of life of patients with advanced kidney cancer.  In foreign countries, preoperative embolization of blood-rich kidney cancer has become routine in some hospitals, which can cause ischemic necrosis of blood-rich tumors through renal artery embolization. In contrast, renal blood supply is an end circulation, which does not lead to ischemic necrosis of adjacent organs. Its indications are: as palliative treatment for those who cannot or do not want to cut down surgically; as preoperative preparation before surgical resection, it can reduce intraoperative bleeding by blocking renal artery blood supply and shrink renal tumor, which helps to cut down surgically and thus improve surgical resection.