People who have a long duration of fever (and the temperature is greater than 38.5 ° C) or repeated high fever (temperature greater than 39.0 ° C), you can take some of the antipyretic and analgesic drugs to reduce fever, the more commonly used drugs are ibuprofen, acetaminophen and so on. Some patients with low fever (less than 38.0°C) can take physical cooling methods, and generally do not need to take antipyretic drugs. The purpose of antipyretic and analgesic drugs is to reduce fever and relieve pain. At this stage, relatively safe antipyretic drugs include ibuprofen suspension, ibuprofen granules, ibuprofen delayed-release capsules, as well as acetaminophen tablets, acetaminophen oral solution and so on. Among them, ibuprofen granules, ibuprofen suspension, and acetaminophen oral solution are suitable for fever-reducing treatment in children due to their good taste, and they can also be used for fever treatment in adults. Adverse effects of ibuprofen preparations mainly include nausea, vomiting, and abdominal pain. Adverse effects of acetaminophen preparations include skin rash and liver damage. Ibuprofen and acetaminophen are contraindicated in patients who are allergic to the ingredients. Fever is the most common clinical symptom and is a normal immune response, which may be associated with viral and bacterial infections, as well as autoimmune disorders. In the antipyretic treatment at the same time, still need to actively treat the primary disease, the specific use of drugs need to be carried out under the guidance of a doctor.