Malignant syndrome must be found to discontinue antipsychotic drugs, while giving supportive treatment, such as cooling, replenishing electrolytes, replenishing fluids, and promoting excretion. Muscle relaxants, such as nifedipine, and bromocriptine, a drug that promotes central dopamine function, can be used, and through proper management, these symptoms will usually be alleviated after a few days. Malignant syndrome is a rare and serious adverse reaction, the clinical features are mainly fluctuations in consciousness, there is a significant impairment of consciousness, there is muscle tonicity, there is hyperthermia, body temperature can be as high as about 40 ℃, at the same time there will be autonomic dysfunction, manifested by sweating, frequent urination, this phenomenon is common drugs such as haloperidol, chlorpromazine endorphine and other such drugs. Factors such as rapid drug dosing, high dosage, dehydration, malnutrition and combined somatic diseases, hot climate, etc. are all related to the occurrence of malignant syndrome. An increase in the concentration of creatine phosphokinase can be found during the onset of the disease, but its elevation is not an indicator for confirming the diagnosis.