The first single-port laparoscopic combined left liver and gallbladder resection in China was successful, which marked that China’s single-port laparoscopic surgery technology reached the international advanced level and made China one of the countries capable of performing single-port laparoscopic complex surgery. The patient, a 44-year-old female, had been found to have multiple hemangiomas in the left lobe of the liver for 5 years and had undergone interventional embolization in a major hospital in Beijing, but the tumor still continued to grow, and the tumor was 8×8cm2 on CT examination, and was combined with gallbladder stones and had a history of recurrent attacks. After systematic examination and preoperative evaluation, the patient met the indications for single-port laparoscopic surgery, and after obtaining the consent of the patient and his family, a transumbilical single-port laparoscopic laparoscopic resection of the left outer lobe of the liver and hemangioma of the left inner lobe of the liver and gallbladder was performed. According to Prof. Rong Liu of PLA General Hospital, who guided the surgery, 1. the current status of single-port laparoscopic surgery, only a few cases of simple surgery such as opening of liver cyst and a small number of single-port laparoscopic cholecystectomy have been reported at home and abroad, and no liver resection has been reported. 2. nearly 300 cases of laparoscopic liver resection have been completed at PLA General Hospital, but most of them are operated by five-port and four-port methods, and only a few are performed by three-port method. Based on the efforts to study anatomy and clinical research, after unremitting exploration, many cases of laparoscopic day surgery of gallbladder have been completed, i.e. patients are hospitalized in the morning for surgery and leave the hospital in the evening, and some of them are single-hole laparoscopic day surgery, which saves medical resources and funds for the country and reduces the physical trauma and economic burden of patients.