Feeling soreness in the kidney may be caused by kidney stones, kidney cysts, kidney tuberculosis, renal insufficiency and other diseases. 1. Kidney stones: Kidney stones may be caused by metabolic abnormalities, urinary tract obstruction, infection, drugs, improper diet and other factors. Patients will have symptoms such as lower back and abdominal pain, hematuria, nausea, vomiting, abdominal distension and so on. 2. Kidney cyst: When the cyst presses the surrounding tissues, symptoms such as soreness, pain and hematuria in the kidney can occur. 3. Renal tuberculosis: the cause of renal tuberculosis is related to Mycobacterium tuberculosis infection, which may also be induced by poor hygiene habits in the living environment, malnutrition, diabetes mellitus, long-term use of immunosuppressive drugs (cyclosporine, tacrolimus) and other factors. There are no obvious symptoms in the early stage of renal tuberculosis, and after the disease progresses, patients may show that the kidneys feel sore and painful. 4. Renal insufficiency: patients with renal insufficiency, caused by various acute and chronic conditions such as gastrointestinal bleeding, heart failure, glomerulonephritis, etc., can clinically manifest as nausea, vomiting, oliguria, anuria, dizziness and other symptoms, and some of the patients can experience back pain, fatigue and poor appetite. There are many reasons that lead to soreness in the kidneys, so it is recommended that patients go to regular hospitals, undergo relevant examinations, and follow the doctor’s instructions for standardized treatment.