Eyelid xanthoma can’t be picked out by needle, otherwise it will easily lead to infection, which may cause serious consequences, and patients need to seek medical treatment in time. Eyelid xanthoma refers to a benign tumor caused by the abnormal metabolism of eyelid fat. Since there are more blood vessel structures under the eyelid skin, and these blood vessel structures are connected with some blood vessels in the skull, if the tumor is picked out with a needle, it is very easy to cause infection, and in serious cases, it will lead to infection in the skull. Since blepharoplastoma has less effect on vision and other things, patients can usually do no special treatment. If it has a greater impact on the patient’s appearance, the patient can go to the hospital in time to be treated by laser or other means. The occurrence of blepharoplastoma may be related to high blood fat, patients should control their diet in daily life and measure blood fat and other related indexes regularly. It is recommended that patients with large blepharoplastoma should consult a doctor to evaluate their condition and follow the doctor’s instructions for treatment.