Vitiligo is a relatively common acquired pigment loss disease, characterized by a lack of melanocytes in the epidermis, mucous membranes and other tissues, with a prevalence of 0.5% to 2% and no significant racial or gender differences. The pathogenesis may be related to genetic, neuroendocrine, autoimmune and other factors. Although there are many treatments for vitiligo, such as medication, laser treatment and epidermal transplantation, but there are still some patients who are not ideal for treatment, such as vitiligo in the eyebrow area, if medication and laser treatment is not ideal, using epidermal transplantation treatment and due to the growth of eyebrow hair, it is difficult to work. But don’t worry, we have autologous single follicle transplantation. The principle of autologous single follicle transplantation for vitiligo is the presence of undifferentiated stem cells in the sheath of the hair root outside the hair follicle, and this stem cell provides a reservoir of melanocytes for vitiligo re-coloration. There are two types of melanocytes in the hair follicle, the inactivated and activated melanocytes, and the inactivated melanocytes can be transplanted to gradually mature with the regeneration of the epidermis to restore color to the eyebrows and the surrounding white skin. The procedure of autologous single follicle transplantation for eyebrow vitiligo is relatively simple, only a small piece of scalp is cut at the back of the occipital area, and then a single hair follicle is separated and implanted in the eyebrow by punching a hole.