Vitiligo is an acquired skin pigmentation disorder that manifests as localized or generalized pigmentation loss. The prevalence is about 0.5%-2% and it occurs all over the world. The immediate cause of this disease is the reduction or dissipation of melanocytes in the affected area. There are several mechanisms leading to melanocyte damage, such as genetic theory, neurofactor theory, immune theory, etc., which are yet to be further confirmed. Parents should consult the hospital when they find skin pigmentation loss in children, and check the body trace elements and immune function and thyroid function if the symptoms are serious. Caution: 1. Take the medication and topical medication on time and according to the dosage, do not change the dosage or the time of taking the medication by yourself. 2, due to the mental burden and psychological pressure is heavy, vitiligo children’s families to educate the children to adjust the abnormal emotions, lift the heart contradiction and pressure. 3, vitiligo patients diet attention: generally no contraindications, it is recommended not to eat VitC effervescent tablets. 4, should avoid trauma and exposure to the sun, especially the progressive stage of the disease. 5, active treatment of concomitant diseases such as Hashimoto’s thyroiditis.