1, vitiligo symptoms: the skin lesions are initially a piece or several hypopigmented spots, the boundary is unclear, gradually expanding into a clear boundary milky white spots, no symptoms. It is a good idea to look at the exposed areas and friction areas, such as the face, neck, back of the hand, wrist, forearm and lumbar-sacral area, the mouth lips, labia, glans, inner mucosa of the foreskin can also be involved. Vitiligo generally appears in three ways, confined to one site or occurring only unilaterally on the trunk (segmental), but most patients have a wide distribution of lesions over multiple areas of the body (generalized), or on the face and distal limbs (facial limb). The hair in the white spots can be white or normal, and sometimes even affect the eye color or retina. The reason for vitiligo: It is not completely clear, there are several theories: genetic susceptibility, autoimmune system abnormalities (accompanied by hypothyroidism, hair loss, pernicious anemia), neuropsychiatric factors (mental trauma and overexertion can increase melanocytes and nervous system interference), melanocyte self-destruction (exposure to phenols and other chemicals), resulting in the inhibition of the tyrosine system or melanin The destruction of melanocytes, which eventually leads to pigment loss at the affected area.