Patients with angina pectoris have a narrowing of the coronary arteries, cardiac neurosis without organic heart disease, mostly caused by psychological stress, the treatment program is significantly different. Angina pectoris is a disease caused by coronary atherosclerosis, the patient’s coronary arteries have different degrees of stenosis, resulting in the patient’s relative or absolute blood supply is insufficient, which can be manifested as angina pectoris, belonging to the organic heart disease, can be given aspirin, atorvastatin, isosorbide nitrate and other drugs, if necessary, to check the coronary arteriography, and may even implantation of stents or coronary bypass grafting. Cardiac neurosis does not have organic changes in the heart, there is no obvious myocardial ischemia occurs during the attack of the disease, the patient’s cause of the disease is mostly related to psychological factors, such as excessive anxiety, stress and fatigue, and so on. Patients with cardiac neurosis should be treated with psychotherapy, and diazepam and other drugs should be given as necessary for sedation. Whether angina or cardiac neurosis, patients need to go to the regular hospital to seek professional help.