Adapalene gel is a topical acne-dissolving drug, which is widely used in clinical practice, and its therapeutic effect has been verified to be relatively obvious. It is a retinoic acid drug, topical application can reduce the hyperkeratosis of the epithelial cells of the hair follicle and the viscosity of the stratum corneum, which in turn reduces the formation of microcomedema and accelerates the discharge of acne, but the effect of its acne removal, but also need specific analysis on a case-by-case basis, as follows: 1, good acne removal effect: in clinical observation, Adapalene gel is effective for non-inflammatory acne, local irritation is small, and safety is relatively high. 2 If the facial skin rash is not simply acne, but also a lot of inflammatory red pimples and pustules, or even a larger number of rashes, in this case, the expected effect may not be achieved through the simple topical application of adapalene gel, and it is usually necessary to combine other topical drugs or oral acne treatment drugs for systematic treatment in order to achieve efficacy.