Adapalene gel does have a certain effect on acne, mainly by acting on the skin surface to speed up skin metabolism, while inhibiting sebaceous gland secretion and reducing the rate of propionibacterium acnes reproduction inside the hair follicle to achieve the effect of acne removal. However, it should be noted that Adapalene gel applied to the skin surface will stimulate the stratum corneum, which will form dry and peeling symptoms, and can only be used at night. Because the drug is a photosensitive drug, its use during the day will affect its efficacy after sunlight exposure, and will also stimulate the stratum corneum to the detriment of health. If the acne symptoms are more serious, it is recommended to take oral isotretinoin 2 times/day, 1 tablet/time, for 1-2 months of continuous treatment can have obvious effects. However, it should be noted that you should not have children within 3 months of taking this medication, otherwise it will easily lead to deformities in the child.