Transaminases are usually referred to as alanine aminotransferase and glutamic aminotransferase. High transaminases can be retested the next day. If the aminotransferase is elevated before strenuous exercise, the result may be normal the next day; if it is caused by liver disease, the aminotransferase will not change greatly and needs to be analyzed specifically. 1. Strenuous exercise: the main cause of aminotransferase elevation is liver cell damage, followed by strenuous exercise before the test, staying up all night, etc. may also lead to transient and slight elevation of aminotransferase. If the transaminases are slightly high due to short-term reasons such as strenuous exercise or staying up late, after a night’s rest, the next day’s retesting may bring them down to normal values. 2. Liver disease: If you suffer from viral hepatitis and other liver diseases, resulting in liver damage caused by elevated transaminases, rest overnight, transaminases usually do not change much. The transaminases may return to normal only after the cause is removed (e.g., by taking entecavir antiviral, etc.) and medications (e.g., glycyrrhizin, etc.) are taken and the liver damage recovers. There may be other causes of high transaminases, such as drug toxicity, cirrhosis, etc. It is recommended to go to the hospital and have the cause clarified with the assistance of a doctor before proceeding with targeted treatment.