The management of menopausal insomnia, palpitations, heartburn and depression includes lifestyle intervention and medication, etc. Remember to consult your doctor in detail to ensure the safety of the management and treatment. 1. Lifestyle intervention: It is recommended to maintain a good mood, listen to music, learn to release inner pressure, avoid overwork; diet should be light and easy to digest diet, avoid eating spicy and stimulating food, you can drink a cup of hot milk before going to bed, hot water to soak your feet and so on, which can help promote sleep; adhere to the appropriate daily exercise to improve the quality of sleep; 2. Medication: If the above lifestyle intervention is not effective, we can consider implementing symptomatic medication under the guidance of a doctor, such as taking the medication glutamine and B vitamins, which have the function of regulating nerves, and if necessary, taking menopausal anaesthesia and estrogen as prescribed by a doctor to help improve the above symptoms of menopause. It is suggested that lifestyle modification requires long-time persistence, patience and confidence, and medication should be strictly in accordance with the doctor’s instructions to avoid blind use of medication.