A reaction may occur in 5 minutes to 1 hour after taking Cephalosporin and drinking alcohol, but the time is not uniform from patient to patient. Cephalosporin generally refers to cephalosporin antibacterial drugs, drinking alcohol after taking this type of drug may produce disulfiram-like reaction, mainly because the drug will interfere with the body’s metabolism of alcohol, resulting in the accumulation of acetaldehyde in the body, leading to the patient to have symptoms of poisoning. Patients may exhibit facial flushing, panic, blurred vision, vomiting, myocardial infarction, acute liver injury, convulsions, etc., which can be severe enough to lead to death. The specific reaction time, most of which is from 5 minutes to ~1 hour, is related to the patient’s dosage of the drug and the amount of alcohol consumed. If the dosage of the drug is higher or the amount of alcohol consumed is higher, the patient’s time to develop a disulfiram-like reaction is likely to be quicker, and the symptoms will be more pronounced. Different patients are different, the exact time of appearance will also be different, and can not be accurately described. It is important to note on a daily basis that alcohol must not be consumed after taking cephalosporins to avoid adverse consequences. If any of the above symptoms appear, you must seek medical attention in time.