Elevation of CA125 with normal ultrasound is clinically common in ovarian malignant tumors, so it should be taken seriously. If it is endometriosis, CA125 may also be elevated, it is best to do a review in half a month. If the value of CA125 after half a month is not much different from the value of the first examination, there is no need to be nervous and it is recommended to exclude the possibility of endometriosis. If the CA125 is reviewed after half a month, there is a doubling of the increase, it is necessary to find the cause of the disease, it is likely to be caused by malignant tumors. If necessary, a CT scan of the pelvis can be done to understand the localization of the ovaries, and then appropriate treatment can be given.