Hands peeling skin is usually eczema, tinea cruris, exfoliative keratolysis and sweating herpes and other causes, the patient can follow the doctor’s instructions for local application of Dinaid ointment, ketoconazole cream and other drugs and oral cetirizine capsules, itraconazole capsules and other drugs for treatment. 1. Eczema: Eczema is usually related to the stimulation of soap, laundry detergent and other chemicals. The patient can use topical dinexidine cream, hydrocortisone butyrate ointment and so on to apply, at the same time oral cetirizine capsules, loratadine tablets and other drugs for treatment, but also pay attention to do not contact with allergenic substances. 2. Ringworm: ringworm is a fungal infection of the hands, patients can follow the doctor’s instructions to use ketoconazole cream and miconazole ointment and other antifungal drugs coated. At the same time oral itraconazole capsules and terbinafine hydrochloride tablets and other treatment. 3. Exfoliative Keratolysis: the etiology is not clear, generally believed to be related to the patient’s excessive sweating, especially sweaty hands and feet. At the beginning of small white spots, and then gradually fused with the appearance of thin dandruff-like exfoliated scales, without obvious itching and pain. Patients can apply topical Vitamin A cream, salicylic acid ointment and other drugs to treat. 4. Sweat herpes: the etiology is not clear, may be too much sweat on the hands. Patients can use topical tretinoin ointment, Eloxon ointment and other drugs to apply. There are many causes of hand peeling, patients should go to the hospital in a timely manner, under the guidance of the doctor to correctly treat, to avoid blind use of drugs to cause adverse consequences.