Growth hormone injections can be given when the epiphysis is about to close, but not yet fully closed, but are not recommended. However, it is not recommended because it may not be as effective and may have side effects. Growth hormone is contraindicated if the epiphysis has closed completely. Growth hormone can promote the growth of bones, internal organs and the whole body, and promote protein synthesis, which can obviously promote the height growth of children. However, growth hormone is contraindicated in children whose epiphyses have completely closed. Growth hormone injections are also not recommended for children whose epiphyses are about to close. It may not be as effective and may lead to benign intracranial hypertension, osteoporosis, and hypothyroidism. Growth hormone is indicated for children with short stature caused by endogenous growth hormone deficiency and chondrodysplasia. If you need to inject growth hormone, it is recommended to go to a regular hospital and inject under the doctor’s diagnosis.