Syphilis rash is usually not itchy. Syphilis rash is mainly seen in patients with stage 2 syphilis, the main symptoms are red spots and papules above the skin, the pressure does not fade, the surface may also be covered with scales, there is no obvious itching discomfort. The vast majority of rashes, allergic dermatitis, etc. will have pain and itching discomfort, so encounter painless and itchy rash needs to be highly valued, especially with a history of unclean sex, need to rule out syphilis. If the syphilis rash, you need to carry out timely anti-infective treatment, such as penicillin, cephalosporin drugs, etc., treatment, but also need to closely review the follow-up. If syphilis rash occurs, it is recommended to go to the hospital in time to clarify, and under the professional guidance of the doctor to take standardized treatment.