Polycystic liver is an autosomal dominant disease; at present, the latest clinical treatments mainly include active observation, surgical treatment and drug treatment. 1. Active observation: no treatment is needed for small, scattered and asymptomatic liver cysts in the early stage, and regular follow-up observation is sufficient. 2. Surgical treatments include puncture and aspiration sclerotherapy for liver cysts, hepatic enucleation, cyst enucleation, liver transplantation and so on. (1) Puncture and aspiration sclerotherapy: it is suitable for single or multiple cysts of large size. After puncture, the fluid in the cyst is aspirated, and then anhydrous ethanol is injected to cauterize the epithelium of the cyst for sclerotherapy to prevent recurrence of the cyst. (2) Open hepatectomy: It is suitable for the treatment of large and superficially located or deeply located residual cysts, which can cause Bard-Ghiarelli syndrome. (3) Cyst enucleation: mainly includes two methods of cyst decapitation and cyst excision. The decapitated cysts need to undergo electrocoagulation or laser coagulation to reduce the probability of recurrence. 3. Drug therapy: Octreotide and Lanreotide belong to the class of growth inhibitor analogs, which can inhibit the level of cAMP produced by the biliary epithelial cells induced by pancreatic secretion, thus inhibiting the growth of hepatic cysts. Other drugs include everolimus and sirolimus. For patients who have been diagnosed with liver cysts, they should go to the relevant departments of regular hospitals and be treated under the guidance of specialized physicians, so as to avoid delays and adverse consequences.