Whether hepatitis B virus carriers have tuberculosis is serious or not depends on the patient’s own condition and cannot be generalized. Hepatitis B patients with liver insufficiency are more prone to liver damage with tuberculosis treatment, and it is recommended that the patients should consult the doctor in time to improve the chest CT, tuberculosis smear, drug sensitivity and other tests to clarify the severity of the disease. Generally, after timely and standardized treatment, hepatitis B carriers’ tuberculosis can be clinically cured, but some patients’ conditions are more serious, and may be complicated by pneumothorax, chronic pulmonary heart disease, etc., and patients with serious illnesses have hemoptysis, which may be life-threatening. Therefore, whether hepatitis B virus carriers have tuberculosis is serious depends on the actual condition of the patient, and cannot be generalized. Hepatitis B virus carriers may have liver insufficiency, which will reduce the body’s tolerance to the drugs absorbed through the liver, even if the liver function has been normal, after suffering from tuberculosis, anti-tuberculosis treatment will make liver damage more obvious compared to other groups of people, and even some patients after stopping the drug, the liver damage will continue to aggravate, and the tuberculosis treatment is more difficult for hepatitis B carriers. It is recommended that the patient should consult the doctor in time and actively cooperate with the doctor to complete further examination to evaluate the condition and further treatment to avoid adverse consequences.