Normal chromosomes usually do not have neurofibromatosis. Because neurofibromatosis itself belongs to chromosomal dominant hereditary disease, chromosomal abnormality will be found in the examination, even if it is acquired neurofibromatosis, it is also related to gene mutation, so chromosomally normal generally will not have neurofibromatosis. The main symptom of neurofibromatosis is the formation of hard lumps in the subcutaneous tissues, the skin color may be brown or milk coffee, and the skin color of some patients may be pink or yellowish brown. When the disease is further aggravated, it may involve the nerves, which leads to nerve compression and is prone to memory impairment and seizures. If you suspect neurofibromatosis, please go to the hospital in time, under the guidance of the doctor to standardize the examination, clear diagnosis and active treatment, so as not to delay the condition.