The patient’s wound is usually fully healed in 4-6h after the wrinkle removal injection and can wash the face. When botulinum toxin is injected for wrinkle reduction, post-operative care is generally divided into two aspects. The first aspect is that local ice can be applied immediately after the injection to stop pain and bleeding, and the syringes and needles used are generally special, very fine, and the damage to the skin and the puncture point is very slight. The second aspect is that because Botox is a neurotoxin, it can act on the junction between the nerve and muscle to weaken the muscle activity, so for the first 3 days after Botox injection, you should avoid rubbing the injection site as hard as possible when washing your face to avoid the diffusion and dispersion of Botox, which can affect the effect of the injection and even cause the stiffness of facial expression. Within 1 week after wrinkle removal, sauna is prohibited, and you should not take drugs containing aspirin or other drugs that hinder the coagulation function of the body, avoid strenuous exercise, pay attention to a healthy work and rest, and ensure sufficient rest.