In life, we criticize a person does not think to do things wrong love to use “take the wrong medicine” to flirt, in fact, is very scientific reason. The drug effects of many drugs can be counteracted by daily diet and poor lifestyle habits and weaken their efficacy. For example: the polycyclic aromatic hydrocarbons in tobacco will also enhance the activity of liver drug enzymes, accelerating the metabolism of drugs in the liver, shortening the half-life of drugs and reducing their efficacy; the popular fruit grapefruit contains a furanocoumarin will affect the function of liver drug enzymes and prolong the degradation time of some drugs, combined use will be some drugs in the body accumulation, inducing drug poisoning; taking cold medicine when drinking high-sugar drinks will greatly inhibit your The appetite will aggravate your anorexia yo. Especially stressed is the antibiotics + wine = disulfiram reaction (commonly known as wine drunken appearance reaction), this reaction is some antibiotics can inhibit the metabolizing enzymes of alcohol, drinking alcohol at the stage of taking drugs may appear weak, dizziness, drowsiness, hallucinations, flushing, headache, nausea, vomiting, blood pressure drop, and even shock and other reactions, serious cases can appear whistling inhibition, deficiency, convulsions, cardiac malfunction and even death. Learn to protect yourself in life and don’t take the wrong medicine. “You’ve taken the wrong medicine, right?” “You’re the one who took the wrong medicine!” When two people have a quarrel, the above dialogue you often hear, at least in the TV series to hear it? In life, there may really be “wrong medicine”, but what we mean by “wrong medicine” here is that there are also contraindications to taking medicine. These medication taboos you know how many clinical studies have shown that diet can affect the absorption, metabolism, excretion and other processes of drugs in the gastrointestinal tract, thus affecting the effectiveness of the drug. Some diets may even have chemical reactions with some drugs, resulting in adverse consequences. So what should I pay attention to during the medication? 1, any drug + smoke = reduce the effectiveness of drugs Smoking will make the lower esophageal muscles and pylorus activity function is weakened, delaying the time of gastric emptying, so that the drug is late to leave the stomach into the small intestine, thus affecting drug absorption. The polycyclic aromatic hydrocarbons in tobacco also enhance the activity of liver drug enzymes, which speed up the degradation of drugs by the liver and reduce the concentration of drugs in the blood, thus affecting the efficacy of drugs. Studies have confirmed that smoking within 30 minutes after taking a drug, the concentration of the drug in the blood is only 1/20 of that of non-smoking. In addition, nicotine also promotes the release of antidiuretic hormone, which affects the discharge of the metabolites of the drug and may induce drug accumulation poisoning. Therefore, it is not advisable to smoke within 30 minutes of taking any medication. 2, most drugs + grapefruit = affect drug metabolism Most drugs require liver liver drug enzymes for metabolism, and grapefruit furanocoumarins will affect the function of liver drug enzymes, prolonging drug degradation time; naringenin and will accelerate the absorption of drugs in the intestine, both factors are likely to increase the concentration of drugs in the blood, thus easily increase the side effects of drugs, may induce a drop in blood pressure, slowed heart rate, and even shock These two factors tend to increase the concentration of the drug in the blood, thus easily increasing the side effects of the drug, which may induce a drop in blood pressure, slowed heart rate, or even shock, and other adverse reactions. Therefore, it is not recommended to consume large amounts of grapefruit during medication. 3, cold medicine + high sugar = affect appetite Recently many people have a cold, poor appetite, poor spirit …… more have to control the high sugar diet. High-sugar food intake too much, will make blood sugar rise, and the body in the process of metabolizing blood sugar need to consume a lot of vitamins, especially the B vitamins. This can easily lead to a reduction or even lack of vitamins in the body, affecting nutrient metabolism, which in turn affects appetite. Not only that, if there is high sugar food in the stomach, it will also make the absorption time of cold medicine containing acetaminophen extended by 2 hours, which affects the function of the drug. Therefore, when taking cold medicine, you should try to avoid high-sugar food, including a variety of sweet drinks. 4, antibiotics + wine = disulfiram reaction Near the Spring Festival, for many people, the most difficult to avoid is the “wine”, but do not advise people taking drugs to drink! Disulfiram is a kind of alcohol withdrawal drug, after taking disulfiram, even if only a little wine, may also appear serious discomfort. The same reaction may occur with antibiotics and alcohol. When alcohol enters the body it is first oxidized to acetaldehyde, then to acetic acid, and finally excreted. However, many antibiotics, such as cephalosporins, isoniazid, ketoconazole, metronidazole file, chloramphenicol, etc., can affect the metabolism of alcohol, leading to the accumulation of acetaldehyde in the body, causing symptoms such as facial flushing, conjunctival congestion, dizziness and headache, nausea and vomiting, irritability, etc. In serious cases, there may be difficulty in whistling, acute liver damage, and even induced death. Therefore, you should avoid alcohol, including any food containing alcohol, such as chocolate, patchouli, wine, etc., during taking antibiotics and within 1 week after stopping them. Within two hours before and after taking antibiotics, you should also avoid eating milk, fruit juice, etc., because milk will reduce the activity of antibiotics, fruit juice rich in fruit acids will accelerate the dissolution of antibiotics, thus affecting the effectiveness of the drug. 5, alkaline drugs + vinegar = neutralization reaction When taking anti-gastric acid drugs such as Gastropin and Daxil, the consumption of vinegar should be reduced. Because the main component of these drugs is sodium bicarbonate, calcium carbonate, aluminum hydroxide and other alkaline substances, while the main component of vinegar is acetic acid, a large number of consumption, the two are prone to neutralization reaction, reducing the effectiveness of the drug. 6, enzyme drugs + hot water, tea = affect the enzyme activity Enzyme drugs are mainly active proteins, when the temperature is too high, its activity will be reduced, or even lose activity, thus affecting the effectiveness of the drug. And the polyphenols in tea are easy to combine with enzymes, reducing the effectiveness of the medicine. Therefore, taking digestive enzymes should choose a slightly lower temperature of plain water, to taste slightly warm (25 ℃) is appropriate. 7, calcium tablets + spinach = affect calcium absorption calcium tablets into the body will be electrolyzed as calcium ions, and spinach contains a large amount of potassium oxalate, which oxalate ions will be combined with calcium ions, preventing the body’s absorption of calcium. Not only that, the two can easily generate calcium oxalate stones. Therefore, it is not advisable to eat spinach within 2 hours before and after taking calcium tablets, or to blanch the spinach for a while before cooking and eating it. In addition, there are many common drugs also have contraindications, such as aspirin avoid alcohol, so as not to aggravate the fever or cause liver damage; ibuprofen avoid coffee, cola, so as not to damage the gastric mucosa. These diets are “good helpers” for drugs. Although some diets have adverse effects on the efficacy of drugs, there are some diets that help enhance the effects of some drugs. 1, high-fat diet: enhance the efficacy of fat-soluble drugs Generally speaking, high-fat diet tends to increase the risk of obesity, hyperlipidemia, atherosclerosis and other risks, is not good for health. However, for people who need to supplement vitamin A, vitamin D, vitamin E and other fat-soluble drugs, if at the same time appropriate consumption of high-fat food, it will help to enhance the effectiveness of drugs. But do not eat a lot of this, so as not to lose more than you gain. 2, vitamin C: to help improve iron deficiency anemia For patients with iron deficiency anemia, it is important to supplement iron. At the same time, you can also properly consume more food rich in vitamin C, because vitamin C can promote the absorption of non-heme iron, helping to enhance the effectiveness of the drug and improve anemia. 3, acidic food: a good “partner” to help digestive drugs human digestion requires gastric acid to stimulate pepsinogen to produce pepsin, and indigestion is usually caused by too little gastric acid. For such people, promoting gastric acid secretion and enhancing pepsin activity is the key. Pepsin is stronger in acidic conditions, so while taking digestive drugs, you can eat more acidic foods, such as: hawthorn, apples, oranges, lemons, etc. 4, high fiber food: help to drive away intestinal worms Many people have had the experience of taking deworming drugs to help remove roundworms and other worms in the body, in fact, in addition to the relevant drugs, appropriate to eat more high dietary fiber food also helps to drive away worms, especially insoluble dietary fiber. Because it can promote intestinal peristalsis, help defecation, to deworming drugs have auxiliary effect. Common high dietary fiber foods are celery, oats, brown rice, beans and so on. In addition, the more familiar “three low diet”, that is, low sugar, low fat, low salt, this diet, to help improve the three high. But it is only a complementary role, not a substitute for drugs.