Usually 40 days without fetal heartbeat and fetal buds cannot or do not require birth control pills. Usually, at 42 days of pregnancy, the embryo buds and primitive heart tube pulsation can be seen. However, some pregnant women have delayed germination and primitive heartbeat due to irregular menstruation and late development of the fertilized egg. Therefore, if a pregnant woman does not have a fetal heartbeat or buds at 40 days without any other abnormalities, she usually cannot or does not need to take medication to prevent the medication from affecting the growth and development of the embryo. If, in addition to this situation, a pregnant woman is found to have a poorly doubled HCG value, an abnormal progesterone level, and is accompanied by symptoms such as vaginal bleeding and abdominal cramps, she needs to be alerted to the possibility of preterm miscarriage. In the case of pre-eclampsia, a comprehensive assessment and treatment with fertility preservation medications should be prescribed by the doctor to prevent miscarriage. It is recommended that pregnant women with no fetal heartbeat or buds at 40 days should adjust their mindset and avoid excessive stress or anxiety. During pregnancy, they should pay attention to rest, eat a balanced diet, and attend obstetric checkups on time.