Taking Leflunomide does not usually affect your teeth. Taking Leflunomide may commonly cause adverse reactions such as diarrhea, itching, hair loss, and rash. If you need to use the medication, you need to use it under the supervision of your doctor. Leflunomide is an immunosuppressant and is used in adults with rheumatoid arthritis to improve the condition. The use of Leflunomide does not usually affect the teeth, but it may cause adverse reactions such as diarrhea, itching, reversible elevation of liver enzymes, hair loss, and skin rash. It is contraindicated for those who are allergic to the components of the drug, those with severe liver insufficiency, pregnant and lactating women. During the administration of the drug it is necessary to pay attention to regular checks of ALT and white blood cells and inability to administer live immunization vaccines. Use with caution in patients with liver damage, immunodeficiency, uncontrolled infections, active gastrointestinal diseases. Patients are advised to use Leflunomide under medical supervision and avoid self-medication.