Rheumatoid arthritis is a chronic systemic immune disease with mainly joint lesions. Its early manifestations are swelling and pain in the small joints of the fingers and wrist joints, and joint stiffness in the morning, which gradually develops into swelling and pain in more than four joints throughout the body and is symmetrical. The pathogenesis of rheumatoid arthritis is still unknown, but it is closely related to genetics, infection and immune system disorders. Modern research has found that if the human leukocyte blood type is HLA-2R4, the disease is likely to develop. The pathological process of rheumatoid arthritis is usually a disorder of the immune system that causes synovitis in the knee joint, which in turn destroys cartilage and eventually leads to bone destruction. Rheumatoid arthritis is not a “terminal illness” and many people surrender psychologically after learning that they are suffering from this disease and have been given a death sentence. The best time to treat the disease is three to six months after the onset of symptoms. If treatment is mistreated or delayed for up to a year, the joints will be damaged and the effectiveness of treatment will be greatly reduced. There are two main types of medications for rheumatoid arthritis: symptomatic non-steroidal anti-inflammatory drugs and disease-modifying drugs, while the latest biologically targeted drugs now offer a bright future for the treatment of refractory rheumatoid arthritis. Although the medical community has a limited number of drugs for rheumatoid arthritis treatment, its therapeutic effect does not depend solely on the amount of technological content of the drugs, but more importantly on the physician’s rational combination of therapeutic drugs, dose selection and the patient’s dependence on the physician. Therefore, rheumatoid arthritis is not terrible, early detection and early treatment, long-term regular medication, do not believe in false advertising, choose the regular hospital specialist clinic is the key to cure rheumatoid arthritis.