(Disclaimer: This article is only for popular science purposes, in order to protect the privacy of patients, the following content of the relevant information has been processed) Abstract: 48-year-old female patient, self-reported joint pain, swelling, limited mobility and other symptoms have existed for more than three years, in the morning when they get up will be more pronounced, and sometimes accompanied by fever symptoms, self-administered antibiotics, fever-reducing medications, the discomfort can not be completely eliminated, and after examination, it was learned that the patient belongs to rheumatoid arthritis, after giving drug treatment, the patient’s condition has been poorly controlled. After examination, it was found that the patient belonged to rheumatoid arthritis, and after medication was given, the patient’s condition has been better controlled. Basic information] Female, 48 years old [Type of disease] Rheumatoid arthritis [Hospital] The First Affiliated Hospital of Xi’an Jiaotong University [Time of consultation] July 2019 [Treatment plan] Medication (Methylprednisolone tablets, Methotrexate tablets, Hydroxychloroquine Sulfate tablets) [Treatment cycle] In-hospital treatment for 5 days, and 2 weeks after discharge to the doctor’s office to review the treatment [Treatment effect] Disease is under control, and the pain and swelling of the joints are basically disappeared, I. Initial Consultation When I first saw the patient, the patient complained that 3 years ago, for unknown reasons, he suddenly felt pain and swelling in the joints, and in the morning, the joints were even more intense, occasionally accompanied by fever, and after taking oral antibiotics or antipyretic drugs, the body would improve in a short period of time, but the above symptoms would occur again, and the discomfort was even more intense. Recently, the patient’s discomfort has become more intense, so she seeks medical attention. I found that the patient had hypothyroidism in the past. After that, I examined the patient and found that the patient had symmetrical swelling, pressure and pain, and restriction of movement in both knees and ankles, and the autoantibody examination found that rheumatoid factor, anti-cyclic citrullinated antibody, and anti-nuclear antibody were positive, so the preliminary diagnosis was rheumatoid arthritis. After diagnosis of rheumatoid arthritis, I communicated with the patient and told him that his condition was relatively serious and he should be hospitalized, and the patient expressed his understanding and stated that he would actively cooperate with the treatment. I first gave the patient methotrexate tablets, hydroxychloroquine sulfate tablets to regulate the immune drugs, anti-rheumatic treatment, and then with methylprednisolone tablets, in order to achieve anti-inflammatory and pain relief. The patient had slight nausea and vomiting during the medication, I told the patient that this was a common adverse drug manifestation, because the discomfort was mild, so I didn’t change other drugs. Third, the treatment effect of the patient in the standardization of medication on the first day, self-reported that the joint pain, swelling, limited movement and other phenomena have improved, the patient’s diet, mental state, urination and defecation are normal. On the 3rd day of drug treatment, when checking the patient’s room, the patient was told that the discomfort in the joints was not very obvious and lighter than that of the previous days. On the 5th day of drug treatment, the disease was under control, and the joint pain, swelling and limitation of movement had basically disappeared, and the patient could be discharged from the hospital normally. After a series of treatment, the patient’s symptoms gradually relieved, I sincerely feel happy for the patient, the patient was discharged from the hospital, I carefully advise the patient rheumatoid arthritis on the patient’s wrists, ankles and other parts of the damage is greater, usually should do a good job of joints parts of the warmth of the joints to prevent the joints from being cold, cold and so on and then triggered or aggravated the condition. In time after the hospital, the drug also need to be taken on time, according to the amount, do not recommend intermittent use of drugs. In addition, patients should rest on time and increase nutritional intake. If there is any discomfort, the patient should go to the hospital for follow-up. The patient in this case did not pay attention to the swelling and pain in the joints initially, which made the uncomfortable symptoms persist and had a certain adverse effect on daily life. However, after systematic treatment, the condition has improved, which shows that the disease can be controlled through active and standardized drug treatment. However, rheumatoid arthritis has a long course and may recur, so patients suffering from this kind of disease should go to the doctor for review on time, and adjust the treatment plan according to the results of each examination in order to better control the disease.