Urine protein (++) indicates possible nephritis. Under normal circumstances, urine protein is negative during routine urine examination, mainly because the amount of protein lost through the filtration membrane of the kidney is relatively small and cannot be detected during routine urine examination. However, if the filtration membrane of the kidney is damaged by some pathological factors, resulting in an increase in its permeability, then the amount of protein lost from here will increase and can be detected in the routine urine test. If urine protein is at (++) suggesting that the 24-hour urine protein quantification may be between 0.5 and 1 gram, it suggests that there is significant kidney damage. At this time, it is necessary to give treatment to control the amount of urine protein. The amount of urine protein may be slower to aggravate the kidney function after control, which is very meaningful for the long-term prognosis of the kidney. It is recommended to further investigate the 24-hour urine protein quantification and the source of urine protein if available. It is necessary to go to the nephrology specialist for further consultation and treatment.