Radiotherapy is usually needed for the late spread of stomach cancer. Patients should actively cooperate with the treatment, and the survival period can be prolonged and the quality of life of patients can be improved through chemotherapy. For patients with advanced spread of gastric cancer, adjuvant radiotherapy and chemotherapy are generally needed. If stomach cancer spreads in advanced stage, it means there are lymph node metastasis or organ metastasis, both of which need adjuvant radiotherapy and chemotherapy. The use of appropriate amount of chemotherapy for patients with advanced gastric cancer can slow down the development of the tumor and improve the symptoms. It has certain short-term curative effect and can prolong the survival time of patients. However, chemotherapy should be determined under doctor’s advice according to the comprehensive situation of patient’s age, risk and willingness to treat. Cooperate with radiation therapy to improve the efficacy and further prevent extensive spread to other parts of the body. When patients have advanced gastric cancer spreading, they should go to hospital for standardized treatment in time to avoid delaying the condition.