Diffuse brain atrophy cannot be cured, but aggressive treatment can slow the progression of the disease and prolong its duration. Diffuse cerebral atrophy includes cerebral cortical atrophy, cerebellar atrophy, and brainstem atrophy. Clinically, patients will show intellectual decline, unsteady walking, balance disorders, personality and behavioral disorders, and some patients will also be accompanied by hemiplegia or epileptic seizures. In the early stage, most of the patients will show dizziness, headache, slow reaction, slow movement and memory impairment, which are also the earliest symptoms of diffuse cerebral atrophy. As the disease progresses, the patient’s memory can be completely lost. Some patients will have personality changes in the early stage, and will be depressed and dislike socializing with others, which will gradually progress to mental retardation and dementia. The principle of treatment is to remove the cause of the disease, improve brain metabolism, inhibit the progress of the disease, for example, can be given to the patient orally Olacetamol capsule, cytarabine sodium tablets, strychnine A, donepezil hydrochloride to improve cognitive function.