Honeycomb pits on the palms of the feet may be associated with plantar warts, fossa keratolytica, tinea pedis, and so on. 1. Plantar warts: they can be induced by long-term friction on the soles of the feet, low immunity, walking barefoot in public places, and skin injuries on the feet. They are usually caused by the human papilloma virus, and some of the skin on the soles of the feet is hyperplastic. Yellowish or brownish-yellow plaques appear on the pressurized areas of the soles of the feet. Initially tiny shiny papules, gradually increasing in size, the soles of the feet may also appear honeycomb-like pits. 2. Fossa keratolytica: generally caused by bacterial infection of the plantar skin, mainly related to living habits, living environment and low immunity. It is usually found in the metatarsal and below the metatarsal, especially in the weight-bearing area. It can also be manifested as small honeycomb-like pits on the soles of the feet, and can be accompanied by excessive sweating and bad odor. 3. Tinea pedis: Because the local sweat glands are partially developed and airtight, if the soles of the feet are in a humid environment for a long time, it may lead to a large number of fungi reproduction. It may be manifested as blistering and peeling of the soles of the feet. Long-term local skin irritation may lead to the appearance of honeycomb pits on the soles of the feet. When there are honeycomb pits on the soles of the feet, it is recommended to consult a doctor in time, follow the doctor’s instructions for further examination, clarify the cause with the help of the doctor, and carry out targeted treatment or therapy.