Chemotherapy-induced nausea and vomiting is one of the biggest problems that plague patients in cancer treatment and a common reason why many family members fear chemotherapy. The incidence and severity of nausea and vomiting in chemotherapy patients are related to the type, dose and regimen of chemotherapy drugs, individual differences of patients, and the psychological activities of patients and family members towards chemotherapy. There are many antiemetic drugs used to treat chemotherapy-related nausea and vomiting, and the effect can reach more than 90%. There are three forms of chemotherapy-induced nausea and vomiting: 1. Acute vomiting: occurs immediately after the use of chemotherapy drugs, with most drugs occurring 1 to 2 hours after administration. 2.Delayed vomiting: it occurs 24 hours after the administration of chemotherapy drugs, mostly in patients who use cisplatin. 3. Anticipatory vomiting: it is a psychological disorder, related to the patient’s psychological condition, the occurrence of chemotherapy vomiting in the past and whether it is handled correctly. Factors affecting chemotherapy-related nausea and vomiting: 1. Different drugs have different emesis-causing intensities: almost all chemotherapy drugs can cause nausea and vomiting, but the most obvious one is cisplatin. 2, the application of chemotherapy drugs: a single use than the reaction is more obvious than the secondary use, foot leaf ethoside intravenous use than oral but less reaction. 3, the dose of chemotherapy drugs: often the greater the dose of the drug used, the more pronounced nausea and vomiting. 4, previous chemotherapy history: patients who have previously received chemotherapy have a greater chance of nausea and vomiting, which is more serious with the original chemotherapy regimen. 5, age and gender: the younger the age, the more likely to occur chemotherapy-related nausea and vomiting, women are more likely to vomit than men. 6, whether combined with other diseases: patients with pain, stomach disease, liver and kidney disease can induce or aggravate nausea and vomiting. Antiemetic drugs: 1. Highly effective drugs: 5-hydroxytryptamine 3 receptor antagonists including endanserone, granisetron, toltesetron, ramosetron, palonosetron, etc. There is also the NK-1 receptor antagonist aripitant. 2. Less potent drugs: gastroflucan, haloperidol, chlorpromazine, promethazine, dexamethasone, methylprednisolone, etc. Psychological treatment: 1, psychological counseling: including psychological guidance of medical staff to explain and the same patient’s psychological feelings persuasion. 2, behavioral therapy: including psychological relaxation (listening to music, watching TV), desensitization therapy (contraction and relaxation techniques).