What causes high total bilirubin and direct bilirubin?

If the patient’s liver function is elevated, total bilirubin and direct bilirubin are elevated, and alkaline phosphatase and GGT are elevated. If all four indicators are elevated and the patient has yellow staining of the skin and sclera, the patient is considered to have obstructive factors in the biliary tract. If the patient has stones, the most likely cause is a stone in the common bile duct. The patient should be actively considered for removal of the common bile duct stones under ERCP and drainage by nasobiliary duct. In case of biliary tumor disease, depending on the location of the tumor, surgery should be considered as the first choice for treatment. After surgery, chemotherapy is routinely administered for 4-6 times. For patients with bile duct compression by tumors in the head of the pancreas, pancreaticoduodenectomy should be considered directly, and chemotherapy or oral chemotherapy should be administered as a routine after surgery. In this case, the stone can be cured by removing the cause of obstruction. For tumor diseases of the biliary tract and tumor diseases of the head of the pancreas that compress the bile duct, the patient is considered to have the possibility of recurrence or metastasis.