According to the primary disease, oral targeted therapeutic drugs should be taken, such as anaerobic bacterial infection caused by the foreskin glans can be oral metronidazole, genital herpes caused by the foreskin redness and swelling can be oral antiviral drugs, gonorrhea caused by the foreskin redness and swelling requires the use of antibiotic drugs. In addition, some patients may also need manipulation reset, surgical removal of excess foreskin. 1. glans penis: for glans penis caused by redness and swelling of the foreskin, the patient is mostly local medication, but in the case of more serious infections, you can use sensitive drugs according to the pathogens, such as bacterial infections oral penicillin, cephalosporin, etc.; anaerobic infections can be oral metronidazole. 2. Genital herpes: If the redness and swelling of the foreskin is caused by genital herpes, patients need to take oral antiviral drugs for treatment, such as acyclovir, vasiclovir and so on. 3. Gonorrhea: Gonorrhea caused by the redness and swelling of the foreskin, need to take oral antibiotic drugs, such as ceftriaxone, macrolide and so on. In addition, if it is the foreskin opening narrow caused by canton caused by the foreskin red and swollen also need to maneuver to reset, followed by circumcision surgery to remove the excess foreskin. Different reasons for the use of medication for the treatment of the swelling of the foreskin will have significant differences, men who find the swelling of the foreskin, it is recommended to consult a doctor in a timely manner, clear the cause of the disease and follow the doctor’s instructions to standardize the use of medication.